Pilot production of monoclonal antibodies

Pilot production of monoclonal antibodies

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Caption: Scientist working with start-up flask of mammalian cell culture used for the commercial production of recombinant proteins or monoclonal antibodies. The initial stage of producing a culture of monoclonal antibodies involves the fusion of a normal antibody-producing cell (a lymphocyte) with a rapidly multiplying tumour cell. The resulting "hybridoma" cells are multiplied in fermenters to produce large numbers of genetically identical copies, each secreting the antibody produced by the original lymphocyte. In this way large amounts of specific antibodies can be produced for use in medicine as vaccines or in diagnostic tests. BRO 3.8.

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Keywords: antibody, biotechnology, cell culture, chemical, culture cell production, flask, genetic, genetics, hybridoma, monoclonal antibo, monoclonal antibody productio, production, production of

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