Vaccinia vaccine for cervical cancer, TEM

Vaccinia vaccine for cervical cancer, TEM

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This image is part of the feature Cervical Cancer Vaccine

Credit: JOHNS HOPKINS MEDICAL INSTITUTIONS/SCIENCE PHOTO LIBRARY

Caption: Cervical cancer vaccine. Colour Transmission Elec- tron Micrograph of Vaccinia viruses genetically engineered into a vaccine against cervical cancer in women. This was developed at Johns Hopkins Medical Institutions, USA. Each year 200, 000 women worldwide die of cervical cancer. Over 90% of this cancer is associated with infection by Human Papilloma Virus (HPV); an E7 antigen in this virus turns normal cervical cells cancerous. The cancer then rapidly multiplies without being recognised by the immune system. The vaccine employs the Vaccinia virus to insert a molecular tag (LAMP-1) in affected cells to make E7 recognisable. This alerts the immune system to kill the cancer cells.

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Keywords: bioengineered, bioengineering, biotechnology, cancer, cervical cancer, cervix, drug, drugs, genetic, genetically engineered, genetics, manufacture, production, transmission electron micrograph, vaccine, vaccinia vaccine

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