Testing purity of AAT from transgenic sheep's milk

Testing purity of AAT from transgenic sheep's milk

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Caption

Transgenic animal research. A researcher testing the purity of a human protein isolated from sheep's milk. The milk came from ewes which had inherited a human gene from a transgenic parent. The gene promotes the ewe's mammary cells to produce alpha-1-antitrypsin (AAT), a human protein. AAT is excreted in the sheep's milk and may later be isolated. In future it may be used in replacement therapy to treat human AAT deficiency, a genetic lung disorder which may lead to fatal emphysema. About 100,000 people suffer from the disorder in Europe and North America. Photographed at Pharmaceutical Proteins Ltd., Scotland.

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