Testing purity of AAT from transgenic sheep's milk

Testing purity of AAT from transgenic sheep's milk

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This image is part of the feature Transgenic Sheep

Credit: PHILIPPE PLAILLY/SCIENCE PHOTO LIBRARY

Caption: Transgenic animal research. A researcher testing the purity of a human protein isolated from sheep's milk. The milk came from ewes which had inherited a human gene from a transgenic parent. The gene promotes the ewe's mammary cells to produce alpha-1-antitrypsin (AAT), a human protein. AAT is excreted in the sheep's milk and may later be isolated. In future it may be used in replacement therapy to treat human AAT deficiency, a genetic lung disorder which may lead to fatal emphysema. About 100,000 people suffer from the disorder in Europe and North America. Photographed at Pharmaceutical Proteins Ltd., Scotland.

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Keywords: aat, alpha-1-antitrypsin, biological, biology, biotechnology, isolation, lab, laboratory, milk, protein, research, science, scientific, sheep, sheep's milk, transgenic, transgenic sheep

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