False-col SEM of hybridoma cell

False-col SEM of hybridoma cell

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Credit: DR JEREMY BURGESS/SCIENCE PHOTO LIBRARY

Caption: False-colour scanning electron micrograph of a hybridoma cell producing a monoclonal antibody to cytoskeleton protein. Monoclonal antibodies are produced by injecting a mouse with an antigen & harvesting its antibody response by removing the B lymphocytes. These are fused with myeloma (tumour) cells taken from a mutant lymphocyte source. The fusion product is called a hybridoma cell. B lymphocytes are short-lived; when fused with tumour cells, which divide indefinitely, the continuous production of antibody is secured. Hybridomas are screened for the required antibody; they are then cloned & produce that antibody. Magnification: x1500 at 35mm size.

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Keywords: antibody to cytoskeleton, biotechnology, drug, engineering, genetic, genetically engineered, genetics, hybridoma cell, monoclonal antibody, monoclonal antibody antibodies

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