Monoclonal antibody screening

Monoclonal antibody screening

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Credit: HANK MORGAN/SCIENCE PHOTO LIBRARY.

Caption: MODEL RELEASED. Technician examines a reagent tray containing monoclonal antibodies, prior to inserting it into an automated screening machine. Monoclonal antibodies are produced by injecting a mouse with an antigen & harvesting its antibody response by removing the B lymphocytes. These are fused with myeloma (tumour) cells taken from a mutant lymphocyte source. The fusion product is called a hybridoma cell. B lymphocytes are short- lived; when fused with tumour cells, which divide indefinetly, the continuous production of antibody is secured. Hybridomas are screened for the required antibody. Once isolated, it is cloned & produces one type of useful antibody.

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Keywords: biotechnology, drug, engineering, female, genetic, genetically engineered, genetics, monoclonal antibody antibodie, monoclonal antibody antibodies, monoclonal antibody screening, of monoclonals, screening, technician, woman scientist

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