Nigel Unwin, ion channel researcher, LMB, Cambridg

Nigel Unwin, ion channel researcher, LMB, Cambridg

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Caption: Nigel Unwin, a scientist at the Laboratory of Molecular Biology, Cambridge, studying the structure of a receptor for acetylcholine, a neurotransmitter. Acetylcholine is released across the junction (synapse) between adjacent nerve cells to bind to receptors on the target cell membrane. A shape change associated with bound neurotransitter/receptor results in pores (ion channels) opening for a fraction of a second. Sodium & potassium ions flood through, altering the electrical potential & firing a second nerve impulse. 3-D composites of electron micrographs were used to build the ion channel model.

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Keywords: acetylcholine receptor, ion channel, neurotransmitter receptor, nigel, plasma mem., plasma membrane, plasma membrne, pore, portraits, potassium channel, sodium channel, surname u, unwin

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