False-colour transmission electron micrograph (TEM) showing mature particles of the Human Immunodeficiency Virus (HIV), the cause of AIDS. Virus particles (in orange) are positioned between two T-lymphocytes, the host cell type in AIDS. Viral replication occurs inside the infected T- cell. New virus particles initially appear as bumps in the host cell membrane which enlarge & finally become detached. Newly-formed virus particles undergo maturation, with the appearance of a characteristic, elongated nucleoid (the dark brown feature visible in centre of some virus particles). Magnification: x22,500 at 6x7cm size, x10,000 at 35mm size.
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