Sindbis virus, computer model

Sindbis virus, computer model

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Caption: Sindbis virus, computer model. Cross section of sindbis virus created using UCSF Chimera molecular modelling software and data from cryo-electron microscopy. It shows the outer glycoprotein shell and the inner protein shell (known as the capsid) separated by a lipid bilayer. The interior of the shell normally contains ribonucleic acid (RNA). Sindbis virus is transmitted by mosquitoes and can cause fever and rash. Cryo-electron microscopes fire beams of electrons at multiple angles at specimens kept at minus 150 degrees Celsius. The resulting 'slices' of data are reconstructed by programs, such as UCSF Chimera, into 3-D models.

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