Sindbis virus, computer model

Sindbis virus, computer model

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Caption: Sindbis virus. Computer model of sindbis virus created using UCSF Chimera molecular modelling software and data from cryo-electron microscopy. It shows the outer glycoprotein shell of the virus. Beneath this layer is a lipid bilayer, an inner protein shell (known as the capsid) and a space containing ribonucleic acid (RNA). Sindbis virus is transmitted by mosquitoes and can cause fever and rash. Cryo-electron microscopy uses beams of electrons, which are fired at multiple angles, to image specimens kept at minus 150 degrees Celsius. The resulting 'slices' of data are reconstructed into 3-D models on computer.

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