Human rhinovirus with antibodies

Human rhinovirus with antibodies

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This image is part of the feature Modelling Nature Deadly Machines

Credit: THOMAS SMITH/DANFORTH CENTER/SCIENCE PHOTO LIBRARY

Caption: Human rhinovirus (HRV) with antibody fragments, computer model. This image was created using molecular modelling software and data from cryo- electron microscopy. It shows the protein shell of the virus (white, grey and orange), known as the capsid, covered by antibody fragments (blue) known as Fab (antigen binding fragment). HRV is the virus that causes the common cold. Cryo-electron microscopes fire multi-angled beams of electrons at specimens that are kept at minus 150 degrees Celsius. The microscope collects 'slices' of data that are reconstructed into 3-D models by computer.

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