False-col TEM of fibrils in mad cow disease

False-col TEM of fibrils in mad cow disease

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Credit: EM UNIT, CVL, WEYBRIDGE/SCIENCE PHOTO LIBRARY

Caption: Bovine spongiform encephalopathy (BSE). False- colour transmission electron micrograph of fibrils, coloured blue, in an extract of fresh brain from a cow infected with BSE, a form of transmissible, slow virus encephalopathy. Human slow virus encephalopathies include Kuru, Creutzfeldt-Jakob disease, & Gerstmann-Straussler syndrome. The agents causing these diseases form a group of virus-like organisms called prions. The fibrils are believed to be aggregations of the major proteins of the infectious agents themselves. Magnification: x67,500 at 6x4.5cm size, x36,300 at 35mm size.

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Keywords: biology, bovin spong. enceph., bovine spong. enceph., bovine spongiform encephalopat, bse, encephalopathy, fibrils, jbu colouring, mad cow disease, microbiology, prion, prions, slow virus, slow virus encephalopathy, transmissible encephalopathy, virology, virus-like

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