Prion causing CJD on CT scan of brain

Prion causing CJD on CT scan of brain

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Credit: ALFRED PASIEKA/SCIENCE PHOTO LIBRARY

Caption: Prion protein. Computer model of the prion protein responsible for causing CJD (Creutzfeldt-Jakob disease) in humans, superimposed on a CT (computed tomography) scan of a brain. The prion is a mutated form of a normal cell protein (PrP). This prion comprises spiralling alpha helices (orange) and straight beta sheets (green). The C and N represent the carbon and nitrogen ends of the amino acid structure respectively. Both BSE and CJD are brain-wasting disorders characterised by progressive dementia and a rapid deterioration in co-ordination, leading inevitably to death.

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Keywords: alpha helices, beta sheets, biology, bovine spongiform, brain scan, bse, cjd, computed tomography, condition, creutzfeldt-jakob disease, ct, encephalopathy, helix, infection, infectious, infective agent, mad cow disease, microbiology, molecular model, neurological disorder, prion, prions, protein, sheet, structure, virology, virus-like

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