3M of human brain in Alzheimer's disease

3M of human brain in Alzheimer's disease

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Credit: SCIENCE PHOTO LIBRARY

Caption: Light micrograph of human brain tissue in Alzheimer's disease, showing its main characteristic histological features of neurofibrillary tangles and a senile plaque. Alzheimer's disease is a form of progressive dementia; the brain is smaller than normal, with degenerative changes affecting the frontal and temporal lobes. Neurofibrillary tangles are masses of thickened filaments in the cytoplasm of neurons (nerve cells) - one is clearly visible at centre top. At bottom left of image is a pale senile plaque, appearing as a mass of dark granules around a non-staining amyloid centre. Magnification: x100 at 35mm size.

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Keywords: alzheimer's, alzheimer's disease, alzheimers disease, amyloid, amyloid senile plaque, amyloidosis, condition, dementia, disease, disorder, healthcare, medical, medicine, neurofibrillary tangle, senile dementia, senile plaque

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