Neurofibrillary tangles, TEM

Neurofibrillary tangles, TEM

M108/0743 Rights Managed

Request low-res file

530 pixels on longest edge, unwatermarked

Request/Download high-res file

Uncompressed file size: 25.0MB

Downloadable file size: 954.7KB

Price image Pricing

Please login to use the price calculator


Credit: JAMES KING-HOLMES/SCIENCE PHOTO LIBRARY

Caption: Neurofibrillary tangles, transmission electron micrograph (TEM). These clumps of protein fibres often appear in the nerve cells of individuals with neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and Pick's disease. These fibres here are made up of tau, a protein associated with microtubules, which are the important skeleton-like structures that support the shape of cells. When a phosphate group is added to the tau molecule, it changes shape and becomes more likely to form aggregates (dark clusters seen in the left corners and lower right) referred to as neurofibrillary tangles.

Release details: Model release not required. Property release not required.

Keywords: aggregating, alzheimer's, alzheimers, biological, biology, black-and-white, brain, clumping, condition, disease, disorder, fibrils, filaments, healthcare, human body, many, medical, medicine, microscope, monochrome, multiple, nerve cells, neurobiology, neurofibrillary, neuroscience, parkinson, parkinsons, pick, picks, plaques, protein, tangles, tangling, tem, transmission electron, transmission electron micrograph

Licence fees: A licence fee will be charged for any media (low or high resolution) used in your project.