This composite of 4 images from an MRI in a child several weeks following a viral illness reveals extensive signal abnormality within the white matter of both cerebral hemispheres. This is a severe form of ADEM = acute disseminated encephalomyelitis. ADEM is a demyelinating disorder similar to multiple sclerosis and is felt to be immune mediated. It is a monophasic disorder and often occurs several weeks following a viral illness or vaccination.
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