Immunofluores. LM of human brain with CJD

Immunofluores. LM of human brain with CJD

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Credit: PROF. J.J. HAUW/SCIENCE PHOTO LIBRARY

Caption: Creutzfeldt-Jakob disease. Immunofluorescent light micrograph of a section through human brain showing Creutzfeldt- Jakob disease (CJD). Two starchy plaques are seen (yellow at centre) amongst brain cells. These plaques have been coloured using antibodies that stick specifically to the virus-like prion particle that causes CJD. CJD results in large vacuoles & plaques appearing in the brain, making it spongy and killing off the tissue. Symptoms include dementia and sudden muscle contractions, leading to death. There is concern that eating beef from "mad cows" may cause CJD in humans.

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Keywords: brain, cjd, condition, creutzfeldt-ja, creutzfeldt-jak, creutzfeldt-jakob, creutzfeldt-jakob dis., creutzfeldt-jakob disea, disease, disorder, encephalopathy, healthcare, light micrograph, medical, medicine, plaque, prion, spongiform encephalopathy

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