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Caption: Multiple myeloma (also known as plasmacytic myeloma or myelomatosis) is a progressive hematologic (blood) disease. It is a cancer of the plasma cell, an important part of the immune system that produces immunoglobulins (antibodies) to help fight infection and disease. Multiple myeloma is characterized by excessive numbers of abnormal plasma cells in the bone marrow and overproduction of intact monoclonal immunoglobulin (IgG, IgA, IgD, or IgE) or Bence-Jones protein. Hypercalcemia, anemia, renal damage, increased susceptibility to bacterial infection, and impaired production of normal immunoglobulin are common clinical manifestations of multiple myeloma. It is often also characterized by diffuse osteoporosis, usually in the pelvis, spine, ribs, and skull.

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Keywords: abnormal bone marrow, anaemia, anemia, bacterial infection, bence jones, bence jones protein, bence-jones, bence-jones protein, blood cancer, blood disease, bone holes, bone marrow, cancer, cell cancer, hematologic, hematologic disease, holes in bone, hypercalcemia, immunoglobulin, impaired production, malignancy, malignant, multiple myeloma, myeloma, myelomatosis, overproduction, plasma, plasma cancer, plasma cell, plasma cell cancer, plasmacytic, plasmacytic myeloma, progessive, progressive disease, renal damage, shoulder x ray, shoulder x-ray, shoulder xray, white blood cell cancer, x ray, x-ray, xray

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