Coloured MRI brain scan showing holoprosencephaly

Coloured MRI brain scan showing holoprosencephaly

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Credit: MEHAU KULYK/SCIENCE PHOTO LIBRARY

Caption: Holoprosencephaly. Coloured magnetic resonance imaging (MRI) scan of a brain (green) with holoprosencephaly. In this congenital condition, a large abnormal ventricle (fluid-filled cavity, pink/blue) forms where the forebrain would norma- lly be. Two healthy ventricles (blue/pink) are at lower left and right. People with this deformity often have no olfactory system (smell), as well as defects in the optic nerve, eyes and pituitary gland. A range of facial deformities reflect the severity of the brain defect, as does the degree of mental handicap. The condition is caused by trisomy, the inheritance of a third chromosome, in this case either chromosome 13, 14, 15 or 18.

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Keywords: brain, brain scan, condition, cut out, cut outs, cut-out, cut-outs, cutout, cutouts, deformity, disease, disorder, healthcare, holoprosence, holoprosencephaly, medical, medicine, mri scan, neuroimaging, retardation, trisomy

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