Deep vein thrombosis. Close-up showing thrombi (dark) or blood clots exposed from the leg of a patient. Deep vein thrombosis is generally caused by a combination of sluggish blood flow together with some condition that increases the natural tendency of the blood to clot. Clots in the leg's veins cause symptoms such as pain, tenderness, swelling, discoloration and ulceration of the skin. If a clot is extensive part of it may break off and be carried up to the heart and then to the lungs where it may block an artery leading to a serious condition known as pulmonary embolism. This image was taken before the leg was amputated.
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