Coloured SEM of oligodendrocyte cell eaten in MS

Coloured SEM of oligodendrocyte cell eaten in MS


Rights Managed


Multiple sclerosis. Coloured scanning electron micrograph (SEM) of a microglial cell (orange) ingesting oligodendrocyte cells (pink, branched) in nerve tissue. This is the process thought to occur in multiple sclerosis (MS). Oligodendrocytes form insulating myelin sheaths around nerve axons in the central nervous system. Microglia normally ingest cell debris and bacteria as part of the body's immune response. In MS they attack oligodendrocytes, possibly triggered by a virus in people with hereditary susceptibility. Destruction of myelin sheaths leads to loss of nerve function. Symptoms include visual and speech defects and paralysis. Magnification: x1580 at 5x7cm size.

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