Artwork of osteoporosis: osteoclast cell eats bone

Artwork of osteoporosis: osteoclast cell eats bone

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Credit: JOHN BAVOSI/SCIENCE PHOTO LIBRARY

Caption: Process of osteoporosis. Illustration of an osteo- clast bone cell in action during removal of bone tissue. An osteoclast (blue, centre) is a giant multi-nucleated cell that normally breaks down the calcified matrix of bone (yellow) during bone growth and formation. In the disease of osteo- porosis, however, more of these cells form. Cells which would normally become osteoblast bone growth cells (pink) coalesce to produce osteoclasts. As a result, bones become brittle and less dense, with a greater risk of fractures. Osteoporosis is most common in post-menopausal women, attributed to a decline in ovarian hormone which helps maintain bone mass. Steroid treatment is effective.

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Keywords: artwork, bone, bone disease, brittle bone disease, cell, condition, disease, disorder, healthcare, in osteoporosis, medical, medicine, osteoclast, osteocyte, osteoporosis

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