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Caption: Osteoporosis. Computer artwork sequence of an osteoclast (green, bone-removing cell) destroying a piece of bone. This process (bone resorption), is a normal part of the continual rebuilding of a human skeleton, but it can get out of control and lead to excessive bone loss in disorders such as osteoporosis. The osteoclast has a ruffled edge that it attaches to the bone (top), secreting acids and enzymes (middle) to remove the mineral and collagen of the bone. The bone is rebuilt by osteoblasts (bone-building cells), but if this does not happen then the bone units (trabeculae) become fragile and may break (bottom).

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Keywords: acid, anatomy, artwork, biological, biology, bone, bone remodelling, bony, cancellous, cell, computer artwork, cutaway, destruction, diagram, disorder, dissolving, human body, illustration, internal, medical, medicine, osteoclast, osteocyte, osteological, osteology, osteoporosis, physiological, physiology, resorption, secreting, section, sequence, skeletal system, spony, structural, structure, tissue, trabecula, unit

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