Whipple's disease, light micrograph

Whipple's disease, light micrograph

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Credit: PR J. L. KEMENY, ISM/SCIENCE PHOTO LIBRARY

Caption: Whipple's disease. Light micrograph of a section through the intestinal villi of a patient with Whipple's disease. This disease is caused by the bacterium Tropheryma whippelli. Some of the bacteria (blue) are seen inside macrophages (purple), white blood cells that phagocytose (engulf) pathogens. Although this disease mainly affects the intestines it may also affect the heart, lungs, joints and brain. In the intestines it causes malabsorption of nutrients, causing weight-loss and nutritional deficiencies. Other symptoms include diarrhoea, abdominal pain, loss of appetite and fatigue. Treatment is with antibiotics. Periodic acid-schiff stain. Magnification: x55 when printed at 10 centimetres tall.

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Keywords: bacteria, bacterial, bacterium, condition, disease, disorder, healthcare, histopathology, infected, infection, intestinal, light micrograph, light microscope, macrophage, macrophages, medical, medicine, pas, pas stain, periodic acid-schiff stain, section, sectioned, small intestine, stain, stained, tropheryma whippelii, tropheryma whippelli, villi, villus, whipple's disease

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