Whipple's disease, light micrograph

Whipple's disease, light micrograph


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Whipple's disease. Light micrograph of a section through the intestine of a patient with Whipple's disease. This disease is caused by the bacterium Tropheryma whippelli . Although this disease mainly affects the intestines it may also affect the heart, lungs, joints and brain. In the intestines it causes malabsorption of nutrients, causing weight-loss and nutritional deficiencies. Other symptoms include diarrhoea, abdominal pain, loss of appetite and fatigue. Treatment is with antibiotics. Stained with eosin and haematoxylin. Magnification: x115 when printed at 10 centimetres wide.

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