Hay fever. Close-up of the eye of a patient showing an inflammation caused by an allergy to grass pollen. Pollen particles attach to receptor sites found on the surface of mast cells which are found in connective tissue. This process triggers the release of chemicals from the mast cells, amongst which histamine is the one responsible for the symptoms related to hay fever. Histamine causes blood vessels to widen, fluids to leak into tissues and muscles to go into spasm.
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