Opioid receptors, PET scans

Opioid receptors, PET scans

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Caption: Opioid receptors. Three coloured Positron Emission Tomography (PET) scans showing the asymmetric distribution of opioid receptors in the human brain. The patient has a lesion in their nervous system. Opiod receptors are located on the exterior of nerve cells (neurons). When pain is detected by the body, endorphins are released and attach to the receptors. They temporarily prevent the nerve cells from firing and therefore provide pain relief. Opioid drugs mimic endorphins. By injecting a patient with an opioid tagged with carbon-11 (radioactive tracer), a colour-coded scan is produced, showing the concentration of opioid receptors from red (highest) through yellow and green to blue (lowest).

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