False-colour homologous pairs of chromosomes

False-colour homologous pairs of chromosomes

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Credit: CNRI/SCIENCE PHOTO LIBRARY

Caption: False-colour karyotype depicting the arrangement of homologous pairs of chromosomes in a female with Down's syndrome (trisomy-21). The syndrome is caused by a chromosomal anomaly: the 21st set having three rather than the normal two chromosomes. The defect results in mental retardation & physical disability. Chromosomes are arranged in numbered pairs according to a standard classification. The male set of chromosomes differs only in the sex chromosomes (far left), which would have shown Y (XY) rather than X (XX). The nucleus of each human cell contains 46 chromosomes in total: 23 from a maternal & 23 from a paternal origin.

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Keywords: chromosomes, condition, disease, disorder, down's, down's syndrome, down's syndrome karyotype, downs, false-coloured, genetic, genetic disorder, healthcare, hereditary, inherited, karyotype, medical, medicine, trisomy 21

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