FISH micrograph of chromosomes in Down's Syndrome

FISH micrograph of chromosomes in Down's Syndrome

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This image is part of the feature New Blood Tests Help Diagnose Down's Syndrome

Credit: JAMES KING-HOLMES/SCIENCE PHOTO LIBRARY

Caption: Pre-natal diagnosis of Down's Syndrome. Fluo- rescence in situ hybridization (FISH) micrograph of chromosomes from a Down's Syndrome foetus. The chromosomes are the elongated structures, coming from the cell nucleus (round). The FISH technique enables chromosomes to be tagged with fluorescent dyes to highlight genetic traits. Here, pink dots highlight 3 copies of chromosome 21, the cause of Down's Syndrome (trisomy 21). This research is being conducted at Cytocell Ltd, a British bio- technology company. Cytocell is developing a kit to detect Down's Syndrome as early as 12 weeks in pregnancy from foetal cells in the mother's blood. FISH is also being used to diagnose cancer genes.

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Keywords: chromoprobe, chromosome 21, condition, cytocell ltd., disease, disorder, down syndrome chromosome, down's syndrome, downs, fish, fish micrograph, fish technique, fluorescence in situ hybridisa, genetic, genetic defect research, healthcare, hereditary, inherited, medical, medicine, pre-natal tst, research, trisomy 21

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