FISH micrograph of chromosomes in Down's Syndrome

FISH micrograph of chromosomes in Down's Syndrome

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Credit: DEPT. OF CLINICAL CYTOGENETICS, ADDENBROOKES HOSPITAL/SCIENCE PHOTO LIBRARY

Caption: Down's syndrome diagnosis. Fluorescence in situ hybridisation (FISH) micrograph of Down's syndrome chromosomes (red) in a foetus' cell nuclei (blue). The FISH technique enables individual chromosomes within the nuclei to be tagged with a fluorescent dye. Here, three copies of chromosome 21 are seen in each nucleus, the cause of Down's syndrome. In a healthy human, each nucleus contains only two copies of chromosome 21. Chromosomes are the parts of a nucleus responsible for carrying the genetic code. Down's syndrome is a genetic disease which causes mental retardation and typically flattened features. It affects around 1 in every 650 babies.

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Keywords: chromoprobe, chromosome 21, condition, disease, disorder, down syndrome nuclei, down's syndrome, downs, fish, fish micr, fish microgra, fish micrograph, fluorescence in situ hybridisa, genetic, genetic defect research, healthcare, hereditary, inherited, medical, medicine, nuclei, nucleus, trisomy, trisomy 21

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