Bacterial synthesis of human haemoglobin

Bacterial synthesis of human haemoglobin

M530/0220 Rights Managed

Request low-res file

530 pixels on longest edge, unwatermarked

Request/Download high-res file

Uncompressed file size: 51.6MB

Downloadable file size: 5.9MB

Price image Pricing

Please login to use the price calculator

This image is part of the feature Artificial Blood


Caption: Synthesis of human haemoglobin for use as a blood substitute using recombinant DNA techniques. Scientists at the U.K. Medical Research Council (MRC) Laboratory of Molecular Biology, Cambridge, and Somatogen Inc., in the U.S. have produced a synthetic haemoglobin, the oxygen-carrying molecule in blood, using genetic engineering techniques on the bacterium E. coli. The bottle at left (NC alpha) contains bacterial cells producing haemoglobin (red colour) whilst the one at right (TG-1) shows no presence of haemoglobin. The need to develop a blood substitute has arisen because of concern over contamination of stocks by pathogens such as HIV, the virus causing AIDS. - Renal toxicity due to dissociation into dimers, overcome by expressing alpha chain as a fused dimer; assembly with 2 beta chains into stable dimers.

Release details: Model release not required. Property release not required.

Keywords: bacteria, blood analysis, blood subs'te, blood substitute, blood testing, clinical, dna, haematology, haemoglobin, haemoglobin blood substitute, healthcare, hematology, hospital test, human blood, medical, medicine, recombinant, recombinant dna, synthetic haemoglobn

Licence fees: A licence fee will be charged for any media (low or high resolution) used in your project.