Simvastatin cholesterol-lowering drug

Simvastatin cholesterol-lowering drug

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Credit: JAMES KING-HOLMES/SCIENCE PHOTO LIBRARY

Caption: Cholesterol-lowering drug. Tweezers holding a pill of the cholesterol-lowering drug Simvastatin. This drug reduces the levels of low-density lipoprotein (LDL) cholesterol in the body. High levels of LDL cholesterol (hypercholesterolaemia) are a major cause of heart disease and strokes. Simvastatin works by blocking the effects of the body enzyme HMG-CoA reductase, which normally causes the body to produce LDL cholesterol from foods. Simvastatin and other similar drugs (known as statins) have also been reported to increase bone density. This means that they could potentially be used as a treatment for osteoporosis (brittle bones), which affects many women after the menopause.

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