LM of a cervical smear showing severe dyplasia

LM of a cervical smear showing severe dyplasia

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Caption: Light micrograph of a cervical smear revealing severe dysplasia (CIN 3), the presence of abnormal, blue-staining cells with large, dark nuclei. The CIN grading refers to a spectrum of potentially cancerous changes (dysplasia) in the stratified squamous epithelium that lines the cervix. CIN 1 corresponds to mild dysplasia, CIN 2 to moderate dysplasia & CIN 3 to severe dysplasia & carcinoma-in-situ. In a normal squamous epithelium, cell division is confined to the basal layer; cells mature & rise towards the surface. Normal superficial cells are pink staining, with small nuclei. Dysplastic cells represent a disruption in the maturation process.

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Keywords: cervical smear, cervix, cin 3, condition, disorder, dysplasia, female reproductive system, gynaecological, gynaecology, gynecology, healthcare, light micrograph, medical, medicine, reproduction pathology, severe, severe dysplasia

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