LM of cervical smear revealing HPV infection

LM of cervical smear revealing HPV infection


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HPV cervical infection. Light micrograph of a cervical smear revealing epithelial cells infected with the human papilloma virus (HPV). HPV causes genital warts & is implicated in the development of cervical cancer. Typical changes to the pink-stained squamous cells include binucl- eation (seen at right) and formation of large haloes around the nuclei (koilocytosis, seen at upper left). Cervical cancer is thought to be caused by a continuation of such cellular changes. In this patient, the smear would be considered "borderline abnormal" and repeated after three months. Papanicolaou stain. Magnification: x400 at 35mm size.

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