Moderate cervical dysplasia. Light micrograph of a section through human cervical epithelium showing moderate dysplasia (abnormal growth) classified as CIN 2. CIN (cervical intraepithelial neoplasia) is the term used to describe malignant changes in the squamous epithelium of the cervix. Here, epithelial cells (upper half of section) have become thickened. Their nuclei (dark, round) have become enlarged and prominent. Cell division is not now confined to the basal (bottom) layer and dysplastic cells have migrated upwards almost to the surface. If untreated moderate dysplasia can progress to cervical cancer. Haematoxylin and eosin stained. Magnification: x200 at 35mm size.
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