Light micrograph of human cardiac muscle fibres, shown in longitudinal section (LS). The cells contain 1-2 nuclei and an extensive branching cytoplasm (synctium). The nuclei are centrally located (in skeletal muscle they are located below the surface of the sarcolemma, the membrane surrounding the muscle fibres), and the regular cross-striations are visible. The intracellular spaces are filled with connective tissue, rich in blood vessels: this reflects the demands on cardiac muscle of strong & continuous contractility. Mag. X 106 (35mm).
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