The cellular activity in an allergic response

The cellular activity in an allergic response

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Caption: Allergy. Artwork showing the cellular activity involved in an allergic response to pollen. Pollen particles (yellow) attach to receptor sites found on the surface of mast cells (round and purple), large cells found in connective tissue. This process triggers the release of chemicals (green spheres) from the mast cells, amongst which histamine is the one responsible for the symptoms related to allergy. Histamine causes blood vessels to widen, fluids to leak into tissues and muscles to go into spasm. Symptoms include eye inflammation and mucus secretion in the upper airways with frequent sneezing.

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Keywords: allergy, anatomy, histamine release, human body, immune system, immunology, mast cell, mast cell activity, pollen

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