Stressed cells

Stressed cells

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Credit: NANCY KEDERSHA/SCIENCE PHOTO LIBRARY

Caption: Stressed cells (image 2 of 2). Immunofluorescent light micrograph of stressed kidney cells. Stress is caused by chemicals, UV light, viral infection and heat shock. The cell enters an emergency mode. TIA-1 and TIAR proteins stop the production (translation) of all proteins, except those needed during stress. The two proteins also assist in the formation of stress granules (blue-green dots), cytoplasmic material where untranslated genetic material (mRNA) can be stored. During these processes, the cell has time to decide whether to make more proteins or shut down activity. The nuclei of the cells (green) and a new protein, FAST K (red), are shown.

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Keywords: animal, biology, cytological, cytology, fast k, granule, immunofluorescence, kidney, light micrograph, light microscope, messenger ribonucleic acid, microtubules, mrna, nuclei, nucleus, physiological, physiology, protein, proteins, rna-binding, stress granules, stressed cells, tia-1, tiar, translation

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