Chemotherapy, light micrograph

Chemotherapy, light micrograph

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Credit: J.W. SHULER/SCIENCE PHOTO LIBRARY

Caption: Chemotherapy. Immunofluorescent light micrograph of a cell treated with taxol (anti-cancer drug). The cell is in the prophase (first) stage of cell division (mitosis). Mitotic cell division usually produces two identical daughter cells. Taxol inhibts mitosis by binding to a protein called tubulin, creating short, stable microtubules (green). Microtubules are essential in mitosis as they control the position of the cell's chromosomes (blue). The short, stable microtubles cannot separate as normal, cell division cannot take place and the cell dies.

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Keywords: blue, cell, cell biology, cell division, chromosome, chromosomes, culture cell, cytoskeleton, dividing, epithelial, green, immunofluorescence, immunofluorescent, light micrograph, light microscope, lung, microtubule, mitosis, mitotic, nature, one, prophase, replicating, reproduction, section, single, taricha granulosa, tubulin microtubules, zoology

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