Structure of RU486 - abortion inducing drug

Structure of RU486 - abortion inducing drug

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Credit: PHILIPPE PLAILLY/SCIENCE PHOTO LIBRARY

Caption: Molecular modelling of a structure for RU486, an abortion-inducing drug, using an Evans & Sutherland PS-300 computer graphics system. RU486 is a steroid hormone similar to progesterone, the production of which by the ovary & placenta is essential to maintain a pregnancy. RU486 binds to cells in the same manner as progesterone does, but blocks the effects of the natural hormone. Two days after an oral dose of RU486, the woman takes a drug called a prostaglandin, which initiates contractions of the uterus that result in the expulsion of the embryo - a drug-induced termination (abortion). RU486 is presently (Nov 1989) only used in clinical trials.

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Keywords: abortion drug, abortion pill, anti-progesterone, cad, chemistry, computer-aided design, drug, high-tech, model, molecular modelling, molecule, ru486, structur, structure, technology

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