AIDS drug AZT

AIDS drug AZT

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Credit: WILL & DENI MCINTYRE/SCIENCE PHOTO LIBRARY

Caption: MODEL RELEASED. AZT drug modelling. Computer molecular modelling of AZT, a drug used in the treatment of AIDS (Acquired Immune Deficiency Syndrome). A space-filling model of a molecule of AZT appears on the screen. AZT is also effective in reducing the complications of secondary infections and in treating the dementia that affects a proportion of AIDS victims. AZT (brand name Retrovir, manufactured by Burroughs- Wellcome) inhibits the action of reverse transcriptase, the AIDS viral enzyme that is crucial to the subversion of a victims's immune system. AZT has side effects; its toxicity to bone marrow may result in patients developing anaemia.

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Keywords: aids drug, azt, cad, chemistry, computer-aided design, drug, high-tech, hiv drug, model, modelling, molecular graphic, molecular modelling, molecule, pharmaceutical, retrovir, scientist, structure, technology, zidovudine

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