FOXO4 protein in complex with DNA

FOXO4 protein in complex with DNA

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Credit: RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY

Caption: FOXO4 protein in complex with DNA. Computer model showing the active site of a molecule of FOXO4 (forkhead box O4, coils) in complex with DNA (deoxyribonucleic acid, spheres). FOX proteins are a family of transcription factors that help regulate gene expression in cell growth, proliferation, differentiation and longevity. They constitute key components of a conserved signalling pathway that connects growth and stress signals to transcriptional control.

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Keywords: active site, alpha helix, anti ageing, anti-ageing, beta sheet, biochemical, biochemistry, biological, biology, catalysing, catalysis, cell growth, chemical, chemistry, coils, complex, complexed, controlling, deoxyribonucleic acid, differentiation, dna, enzyme, forkhead box, fox, fox-o4, foxo, foxo4, gene expression, genetic, genetics, helices, longevity, molecular model, molecule, o4, proliferation, protein structure, proteins, proteomics, quaternary structure, random coil, regulating, regulation, regulator, secondary structure, sheets, signal, signalling pathway, signals, stress, tertiary structure, transcription factor, transcriptional control

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