Foetal bone formation, light micrograph

Foetal bone formation, light micrograph

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Credit: DR KEITH WHEELER/SCIENCE PHOTO LIBRARY

Caption: Foetal bone formation. Light micrograph of a longitudinal section through a foetal finger, showing bone formation (ossification). The finger bones (phalanges) are initially formed of cartilage. The ossification is endochondral (as opposed to intramembranous) and starts from the middle of the cartilage and proceeds outwards. Osteoblasts secrete collagen fibres to form a matrix with calcium salts, forming the trabeculae of spongy bone (red-orange mesh). The articular cartilage (yellow) at the ends of the bone, undergoes a secondary ossification, and also forms cartilage discs for the joint. Magnification: x13 when printed 10 centimetres wide.

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Keywords: anatomical, anatomy, articular cartilage, biological, biology, bone, bone formation, bone matrix, cartilage, collagen, developmental biology, endochondral ossification, fetus, finger, finger bone, foetal, foetus, gestation, hand, healthy, histological, histology, human body, joints, light micrograph, light microscope, lm, longitudinal section, normal, ossification, osteoblast, osteoblasts, osteology, phalanges, phalanx, physiological, physiology, pregnancy, section, sectioned, spongy bone, tissue, white background

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