First-line drugs for tuberculosis

First-line drugs for tuberculosis

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Caption: MODEL RELEASED. First-line drugs for tuberculosis (TB) treatment. Four drugs are used in combination for first-line treatment. These are rifampicin, isoniazid and pyrazinamide, combined into one tablet and marketed as Rifater, and ethambutol. This combination of drugs is taken for two months, followed by another four months of rifampicin and isoniazid. This combination therapy is used to prevent the bacteria from becoming resistant to any of the drugs. As the drugs have different mechanisms of action using a combination is also more likely to clear all the bacteria from the body. TB is cased by the bacterium Mycobacterium tuberculosis, which is spread by coughing and sneezing. It infects the lungs creating primary tubercles, nodular lesions of dead tissue and bacteria. The bacteria may enter the blood or lymph system and spread to other organs of the body.

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