Melanosis Coli

Melanosis Coli

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Credit: DAVID MUSHER/SCIENCE PHOTO LIBRARY

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Caption: A benign condition of the colon due to deposition of melanin, a black pigment, in the colon. This is associated with laxative abuse, particularly anthracene type cathartics: cascacara, senna, aloe, rhubarb and frangula. Cessation of the laxative results in disappearance of the pigmentation. Lymph follicles and polyps do not take up the pigment.

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Keywords: aloe, benign colon lesion, cascara, chronic constipation, colonoscopy, diarrhoea, frangula, laxative abuse, melanin, melanosis, pigmentation of the colon, rhubarb, senna

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