Melanosis Coli with Benign Polyp

Melanosis Coli with Benign Polyp

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Credit: DAVID MUSHER/SCIENCE PHOTO LIBRARY

Caption: A benign condition of the colon due to deposition of melanin, a black pigment, in the colon. This is associated with laxative abuse, particularly anthracene type cathartics: cascacara, senna, aloe, rhubarb and frangula. Cessation of the laxative results in disappearance of the pigmentation. Lymph follicles and polyps do not take up the pigment. Removal of this polyp revealed it to be a benign hyperplastic polyp.

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Keywords: aloe, benign colon lesion, benign polyp, cascara, chronic constipation, colon polyp, colonoscopy, diarrhoea, frangula, hyperplastic polyp, laxative abuse, melanin, melanosis, pigmentation of the colon, rhubarb, senna

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