Pustular Rash induced by chemotherapy

Pustular Rash induced by chemotherapy

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Credit: DNA ILLUSTRATIONS/SCIENCE PHOTO LIBRARY

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Caption: This illustrates cutaneous toxicities in the skin due to chemotherapy that target the epidermal growth factor receptors on basal keratinocytes in the epidermis of the skin. The drugs cause EGFR-mediated signalling (lower right) that induce growth arrest, apoptosis (cell death), decreasing cell migration, increasing cell attachment and differentiation, and stimulating inflammation, all lead to cutaneous papulopustular rash.

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Keywords: artwork, basal cell, basal keratinocytes, cgi, dermis, digitally generated, egfr pathway, epidermal growth factor receptor, epidermis, graphic, hair follicle, illustration, medical illustration, papulopustular, pus, rash, subcutaneous, tyrosine kinase inhibitors

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