AKT1 human enzyme molecule

AKT1 human enzyme molecule

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Credit: RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY

Caption: AKT1 human enzyme molecule. Computer model showing the secondary structure of a molecule of RAC-alpha serine/threonine-protein kinase (AKT1, white), interacting with a substrate peptide and inhibitor. Protein kinase enzymes modify other proteins by chemically adding phosphate groups to them (phosphorylation). AKT1 is a critical mediator of cell death (apoptosis) in neurons (nerve cells) through the phosphorylation and inactivation on the apoptotic machinery.

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