AKT1 human enzyme molecule

AKT1 human enzyme molecule

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Credit: RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY

Caption: AKT1 human enzyme molecule. Computer model showing the quaternary structure of a molecule of RAC-alpha serine/threonine-protein kinase (AKT1, white), interacting with a substrate peptide and inhibitor. Protein kinase enzymes modify other proteins by chemically adding phosphate groups to them (phosphorylation). AKT1 is a critical mediator of cell death (apoptosis) in neurons (nerve cells) through the phosphorylation and inactivation on the apoptotic machinery.

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Keywords: active site, akt1, apoptosis, apoptotic, biochemical, biochemistry, biological, cell death, chemical, chemistry, critical mediator, enzyme, human, inactivation, inhibitor, interacting, interaction, molecular biology, molecular model, molecule, molecules, nerve cells, neuron, neurone, neurones, neurons, phosphorylation, protein, protein kinase, proteins, proteomics, quaternary structure, rac-alpha serine/threonine-protein kinase akt1, substrate, target, tertiary structure

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