Nucleosome core particle bound to DNA

Nucleosome core particle bound to DNA

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Credit: LAGUNA DESIGN/SCIENCE PHOTO LIBRARY

Caption: Nucleosome core particle bound to DNA. Molecular model showing a nucleosome core particle (green and blue) bound to a strand of DNA (deoxyribonucleic acid, orange). A nucleosome is the basic unit of DNA packaging in eukaryotic cells, consisting of a segment of DNA wound in sequence around four histone protein cores. The nucleosome core particle consists of 145 base pairs of DNA wrapped in left-handed superhelical turns around a histone octamer consisting of 2 copies each of the core histones H2A, H2B, H3, and H4.

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