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Caption: Marrow hyperplasia in skull and bone of a child with thalassemia, an inherited blood disease. In thalassemia the genetic defect, which could be either mutation or deletion, results in reduced rate of synthesis or no synthesis of one of the globin chains that make up hemoglobin.

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Keywords: abnormal, blood disease, blood disorder, bone, bone marrow, child skull, child'ss skull, condition, disease, disorder, distorted skull, distorted skull plates, faulty hemoglobin, gross pathology, gross specimen, hemoglobin, hyperplasia, illness, long bone, marrow hyperplasia, medical, medicine, mutation, pathology, science, skull plates, thalassaemia, thalassemia, unhealthy

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